The work will involve synthesis of derivatives of a natural product and examination of cellular effects, in order to identify a biologically suitable site for the attachment of covalent modifier tag. The tagged derivative will be used to pull out interacting proteins from cell lysates and target identification carried out through mass spectrometry-based proteomics. The PDRA will also synthesise nanoscale polyprodrug delivery systems and examine their release profile and biological activity.

You will be involved in the design and execution of the experimental work and will liaise directly with counterparts in Viet Nam through emails and Skype and attending joint project meetings.

The post is EPSRC funded through a Global Challenges Research Fund. As this is a collaboration with Vietnamese partners, travel to Viet Nam will be a key component of the post.

As Postdoctoral Research Associate in Chemical Biology you will:

• Carry out the research as documented in the proposal, following a research plan agreed with the project principal investigator, in order to deliver the specific aims of the grant
• Organise and manage a programme of laboratory work with reference to the research project work-plan, deliverables and milestones, outlined in the grant
• Disseminate results to the scientific community via publications in high quality journals and presentations at international conferences
• Contribute to research funding applications for extension of this project or related projects

To be successful in this role you will have:

• PhD (awarded or near completion), in a relevant area of chemistry, or equivalent level of experience and expertise
• Extensive practical experience in organic synthesis
• Track record of publication of research articles in high quality journals
• Experience in summarising and presenting results
• Good  interpersonal skills and ability to communicate technical information

The School of Physical Sciences (SPS) is a vibrant, dynamic and expanding interdisciplinary school covering forensic science, physics and chemistry. SPS is a dynamic School achieving national and international excellence in both teaching and research.

The School of Biosciences welcomes staff and students from all over the world and has a strong commitment to equality. They are proud of their collaborative approach and friendly and supportive atmosphere and encourage everyone to contribute and reach their full potential. 

Interviews will take place remotely during the week commencing 08 June 2020

Informal enquiries can be directed to: [email protected]

If you require further information regarding the application process, please contact The Resourcing Team on [email protected] quoting ref number: STM-138-20.

Please note - Applications must be made via the University’s online application system. CVs or details sent directly to the department or via email cannot be considered.